CCM Nepal has a Committee composed of 17 voting members representing different sectors and constituencies; Government of Nepal (GoN), civil society/NGOs working in HIV/AIDS, TB and Malaria, people living with or affected by HIV/AIDS, TB and Malaria; community organizations; the private sector; professional associations; research institutes, universities, media and international agencies including multilateral or bilateral agencies, international donors and international NGOs.The Executive Secretary of the CCM Secretariat is non-voting member of CCM Nepal.
CCM Nepal has an Executive committee of five members with a chair and vice- chair who are assisted by an executive secretary. The Executive Secretary executes the day to day tasks and facilitates various decisions of the CCM. The hierarchy of authority in the CCM is as follows: CCM; Executive Committee; Chair; Vice Chair. Within this hierarchy, any party can be over-ruled by parties higher in the hierarchy. The fomer CCM Chair was from the Ministry of Health and Population- Government of Nepal and the former Vice- Chair was from people living with disease, HIV (PLWD).